Chondrosarcoma in Hereditary Multiple Exostosis

  • L Solomon


Chondrosarcoma is believed by Jaffe to occur in as many as 25% of patients with hereditary multiple exostosis. This subject is discussed in the light of the author's experience of 25 cases of suspected or proved malignancy in multiple exostosis. The cases are divided into three categories: those in which a chondrosarcoma was suspected on the basis of the size of the tumour or the degree of calcification of the cartilage cap; those which showed progressive enlargement of a tumour after the end of the growth period; and those with unequivocal radiological and histological signs of malignant change. A critical examination of the diagnostic criteria is presentedand a rational  approach to treatment is suggested.

S. Afr. Med. J., 48, 671 (1974).

Author Biography

L Solomon
Department of Orthopaedic Surgery, University of the Witwatersrand, Johannesburg

Journal Identifiers

eISSN: 0256-95749
print ISSN: 2078-5135