South African Medical Journal

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A Carbenicillin R Factor from Pseudomonas aeruginosa

AJ van Rensburg, MJ de Klerk


Of 64 carbenicillin-resistant Pseudomonas aeruginosa strains 40 transferred this resistance to Escherichia coli. R factor RP-638 isolated from Ps. aeruginosa strain 638 conferred resistance to ampicillin, carbenicillin, kanamycin, neomycin and tetracycline. This R factor was transferred at frequencies 01 10-7 to 10-4 between v:Jrious strains of Pseudomonas, Proteus and Alcaligenes, and coexisted stably with both fi+ and fi- R factors. Electron microscopy showed the presence of circular DNA molecules with an average contour length of 19,3 ± 0,6 µm.

S. Afr. Med. J., 48, 1187 (1974).

AJOL African Journals Online