The Place of Splenectomy in Haematological Disorders

  • D Gale
  • P Sacks
  • S Lynch
  • TH Bothwell
  • W Bezwoda
  • K Stevens

Abstract

The results of 67 consecutive splenectomies carried out in patients attending the Haematology Clinic at the Johannesburg Hospital between 1965 and 1972 are reported. Forty patients underwent splenectomy because of the presence of cytopenia due in part at least to hypersplenism. The best results were achieved in 21 patients who were considered to have cytopenia due to a disordered immune mechanism and in whom the  spleen was usually normal in size or only minimally enlarged. In addition, satisfactory results were obtained in 17 patients with a large spleen and pancytopenia. In this group the least satisfactory results were recorded in patients with advanced myelofibrosis. The results of splenectomy were also disappointing in 9 patients with lymphoma and other haematological malignancies. Sixteen diagnostic splenectomies were performed: 11 were done as part of a 'staging' laparotomy, for lymphoma. Although there was no operative mortality in this study, half the patients suffered complications, and in 16% of them they were severe, being usually the result of haemorrhage and/or infection.

S. Air. Med. J., 48, 1240 (1974).

Author Biographies

D Gale
Haematology Clinic, Johannesburg Geueral Hospital, and Departmeut of Medicine, University of the Witwatersrand, Johannesburg
P Sacks
Haematology Clinic, Johannesburg Geueral Hospital, and Departmeut of Medicine, University of the Witwatersrand, Johannesburg
S Lynch
Haematology Clinic, Johannesburg Geueral Hospital, and Departmeut of Medicine, University of the Witwatersrand, Johannesburg
TH Bothwell
Haematology Clinic, Johannesburg Geueral Hospital, and Departmeut of Medicine, University of the Witwatersrand, Johannesburg
W Bezwoda
Haematology Clinic, Johannesburg Geueral Hospital, and Departmeut of Medicine, University of the Witwatersrand, Johannesburg
K Stevens
Department of Haematology, School of Pathology, South African Institute for Medical Research and University of tbe Witwatersrand, Johannesburg
Published
2018-03-17
Section
Articles

Journal Identifiers


eISSN: 0256-95749
print ISSN: 2078-5135