Some implications of current therapy in leukaemia
AbstractImproved survival in acute leukaemia follows aggressive combination chemotherapy based on a proper understanding of tumour cell kinetics and principles of modern pharmacology. Such cytoreduction regimens reduce tumour mass to a level at which eradication by immune mechanisms becomes feasible, a fact presently being exploited by immunotherapy programmes. Further improvement is possible by the judicious use of sophisticated support facilities such as laminar flow isolation areas and blood fraction separators, but the cost and expertise of operating such facilities limits availability to a few specialised centres. Logically, patients with acute leukaemia should have the benefit of management in these units.
S. Afr. Med. J., 48, 1573 (1974).
Copyright remains in the Author’s name. The work is licensed under a Creative Commons Attribution - Noncommercial Works License. Authors are required to complete and sign an Author Agreement form that outlines Author and Publisher rights and terms of publication. The Agreement form should be uploaded along with other submissions files and any submission will be considered incomplete without it [forthcoming].
Material submitted for publication in the SAMJ is accepted provided it has not been published or submitted for publication elsewhere. Please inform the editorial team if the main findings of your paper have been presented at a conference and published in abstract form, to avoid copyright infringement. The SAMJ does not hold itself responsible for statements made by the authors.
Previously published images
If an image/figure has been previously published, permission to reproduce or alter it must be obtained by the authors from the original publisher and the figure legend must give full credit to the original source. This credit should be accompanied by a letter indicating that permission to reproduce the image has been granted to the author/s. This letter should be uploaded as a supplementary file during submission.