A double-blind gastroscopic study of a Bismuth-peptide complex in gastric ulceration

  • M G Moshal


Forty courses of treatment with bicitropeptide (BCP) were administered to 30 patients with gastric ulcers, in a double-blind crossover trial. Healing was judged gastroscopically after 4 weeks, at which time 79% of ulcers had healed on BCP and 35% on placebo (P<O,Ol). There were no side-effects. Bicitropeptide is a bismuth-protein complex, active at a pH of less than 4. A protective 'protein-bismuth complex' layer is said to be formed over the ulcer.

S. Afr. Med. J., 48, 1610 (1974).

Author Biography

M G Moshal

Gastro-intestinal Unit, Department of Medicine, University of Natal and King Edward VIII Hospital, Durban


Journal Identifiers

eISSN: 0256-95749
print ISSN: 2078-5135