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Treatment of severe parkinsonism with L-Dopa


H.E. Reef
R. Joffe
H. Milletz

Abstract

The beneficial effect of L-dopa in the treatment of Parkinson's disease is confirmed, although the success rate was slightly lower than reported in other studies. This can be explained by the fact that only elderly and very severely disabled patients were treated. Akinesia and rigidity were the symptoms which responded best to this form of treatment. Tremor responded poorly and most of the therapeutic failures were in patients where tremor was the major complaint. It is possible that this symptom may respond to very much larger doses.


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eISSN: 2078-5135
print ISSN: 0256-9574