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Adult metachromatic leucodystrophy


Gillian Cole
N.S.F. Proctor

Abstract

A case of adult metachromatic leucodystrophy, the first described in South Africa, is reported. A 28-year-old, White South African-born male developed mental and neurological signs which started 4 years prior to his admission to Sterkfontein Hospital. His course was progressively downhill, and by the time of his death he was profoundly demented. An autopsy was performed, and the diagnosis of adult metachromatic leucodystrophy was made histologically. A brief summary of the disease is given.

S. Afr. Med. J. 48, 1371 (1974).

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eISSN: 2078-5135
print ISSN: 0256-9574