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Acid-base balance of cerebrospinal fluid in acute uncompensated metabolic acidosis of infancy


N. Buchanan
C. Eyberg

Abstract

The acid-base of cerebrospinal fluid was studied in infants  with an uncompensated metabolic acidosis due to gastroenteritis. No clinical prognostic value could be obtained from these analyses. Cerebrospinal fluid bicarbonate behavell differently in infants who were alert as opposed to those in stupor. Cerebrospillal fluid bicarbonate rose relative to arterial bicarbonate in the alert patients, but with the advent of stupor, returned to the levels seen in the control patients. The possible significance of this finding is discussed.

S. Afr. Med. J. 48, 1471 (1974).

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eISSN: 2078-5135
print ISSN: 0256-9574