PROMOTING ACCESS TO AFRICAN RESEARCH

Tropical Journal of Obstetrics and Gynaecology

Log in or Register to get access to full text downloads.

Remember me or Register



Perinatal Outcome in Patients With Pre-Eclampsia in Benin City, Nigeria

Alphonsus N Onyiriuka, Angela A Okolo

Abstract


Objective: To determine the prevalence of pre-eclampsia and examine its influence on perinatal outcome among Nigerian women.

Methods: Among 3780 deliveries over a two-and-half year period, 212 singleton infants were born after preeclamptic pregnancies. We compared the perinatal outcome with those of 636 control infants. Pre-eclampsia was defined as (1) an increase in either systolic or diastolic blood preasure (BP) greater than 30mm Hg or 15mmHg respectively above the booking BP plus proteinuria ( > 1+) without simultaneous urinary tract infection. (2) an intrapartum BP > 140 /90mmHg obtained on at least two occasions not less than 6 hours apart during delivery plus presence of proteinuria as indicated in (1) above.

Results: The prevalence of pre-eclampsia was 5.6%; corresponding to 77.9% of all cases of hypertensive disorders in pregnancy. Pre-eclampsia occurred most frequently among women aged 20-24 years (2.7%); corresponding to 48.6% of all cases and whose parity were zero (3.6%); corresponding to 64.2% of all cases. The perinatal mortality rate, the preterm delivery rate and the incidence of birth asphyxia were separately significantly higher in mothers with pre-eclamptic pregnancies than in controls. Mean birth weight was significantly lower in infants delivered after pre-eclamptic pregnancies (2995 + 340g) than after control pregnancies (3105 + 301g). Presence of heavy proteinuria (= 3+) potentiated the adverse effects of pre-eclampsia on perinatal outcome.

Conclusion: Pre-eclampsia commonly complicates pregnancy in young primiparous women. It affects the fetus adversely resulting in fetal growth restriction, preterm delivery, birth asphyxia and sometimes, fetal demise.
Key Words: Pre-Eclampsia, Hypertension, Pregnancy, Proteinuria

[Trop J Obstet Gynaecol, 2004; 21:148-152]



http://dx.doi.org/10.4314/tjog.v21i2.14490
AJOL African Journals Online