Main Article Content

Antioxidant, Iron-chelating and Anti-glucosidase Activities of <i>Typha domingensis</i> Pers (Typhaceae)

T Chai
M Mohan
H Ong
F Wong


Purpose: To evaluate the phytochemical profile as well as in vitro  antioxidant, iron-chelating, and antiglucosidase activities of Typha  domingensis Pers. (Typhaceae)
Methods: Total polyphenols, flavonoids, hydroxycinnamic acids, and pro-anthocyanidins in the respective aqueous extracts of male and female flowers, and fruit of T. domingensis were determined by established  procedures. Antioxidant activity was evaluated by superoxide anion radical and nitric oxide scavenging assays. Iron chelating activity was assessed using a ferrozine-based assay. Antiglucosidase activity was determined using 4-nitrophenyl α-D-glucopyranoside as a substrate.

Results: Phenolic contents decreased in the following order: fruit > female flower > male flower. Superoxide scavenging half-maximal effective   concentration (EC50) of fruit, female flower and male flower extracts was 3.5, 4.8, and 28.2 mg dry matter (DM)/ml, respectively, while nitric oxide scavenging EC50 of fruit, female flower and male flower extracts was 0.16, 0.65, and 0.95 mg DM/ml, respectively. On the other hand, iron chelating EC50 of female flower, male flower and fruit extracts was 4.86, 6.43, and 10.88 mg DM/ml, respectively. Only the fruit and female flower extracts  exhibited anti-glucosidase activity, with EC50 of 0.75 and 5.07 mg DM/ml, respectively.

Conclusion: The fruit and female flower extracts of T. domingensis are promising sources of natural antioxidants, iron chelators, and glucosidase inhibitors.

Keywords: Typha domingensis, Antioxidants, Iron-chelation,  Anti-glucosidase activity.

Journal Identifiers

eISSN: 1596-9827
print ISSN: 1596-5996