Determination of Chemical Constituents of the Marine Pulmonate Slug, Paraoncidium reevesii
Purpose: To isolate and identify the chemical components of Paraoncidium reevesii.
Methods: Silica gel column chromatography was used to isolate the components from petroleum ether and ethyl acetate fractions of the acetone extract, and the structures of the compounds were derived from 1H-nuclear magnetic resonance (1H-NMR), 13C-nuclear magnetic resonance (13C-NMR) and mass spectrometry (MS) analyses and also with the aid of literature data for authenticated samples.
Results: Cholesterol (1), baconipyrone D (2), chimyl alcohol (3), batyl alcohol (4), á-monpalmitin (5), stearic acid (6), 3-indolecarboxylic acid (7), uracil (8), thymine (9), uridine (10), thymidine (11) were isolated from the marine slug (Paraoncidium reevesii).
Conclusion: All the isolated compounds are being reported here for Paraoncidium reevesii for the first time. The results provide base data for further study of the Onchidiidae as a Chinese traditional remedy for asthma and athlete’s foot.
Keywords: Mollusk, Paraoncidium reevesii, Baconipyrone D, Batyl alcohol, Chimyl alcohol Onchidiidae, Marine Pulmonate, Slug, Asthma, Athlete’s foot
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