Tropical Journal of Pharmaceutical Research

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Effect of Carvacrol on Salmonella Saintpaul Biofilms on Stainless Steel Surface

NS Uchida, R Grespan, M Piovezan, EC Ferreira, MM Junior, RKN Cuman, JMG Mikcha


Purpose: To evaluate the effect of carvacrol against Salmonella Saintpaul biofilms on stainless steel surface.
Methods: The effects of carvacrol on planktonic cells were evaluated by determining the minimum inhibitory concentration and minimal bactericidal concentration. The action of carvacrol on Salmonella Saintpaul biofilms on stainless steel surface was evaluated on established biofilm and on biofilm formation by counting the number of bacterial cells that adhered to the surface using scanning electron microscopy.
Results: The antimicrobial activity of carvacrol in planktonic cells of Salmonella Saintpaul was observed. The highest inhibitory effect of carvacrol was observed on biofilm formation at different subinhibitory concentrations.
Conclusion: Carvacrol reduced the number of bacterial cells that adhered to stainless steel surface, making it a potential compound for Salmonella Saintpaul control.

Keywords: Salmonella spp, Biofilm, Planktonic cells, Carvacrol, Stainless steel
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