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Tropical Journal of Pharmaceutical Research

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Potential Beneficial Effects of Tulbaghia violacea William Henry Harvey (Alliaceae) on Cardiovascular System - A Review

I Raji, K Obikeze, P Mugabo

Abstract


Tulbaghia violacea William Henry Harvey (Harv. Alliaceae) is a small bulbous herb belonging to the family Alliaceae. It is used in South Africa to treat fever, colds, asthma, paralysis, and hypertension. Meanwhile, cardiovascular disease accounts for about 30 % of total global death, with most of these deaths occurring in low and middle-income countries. Furthermore, people in low-income countries are still largely dependent on plants in their surroundings for both prophylaxis and treatment of diseases, partly due to limited access to and cost of pharmaceuticals, and folkloric evidence of the potency of medicinal plants and/or local belief systems. Therefore, the present review aims to proffer possible ways by which T. violacea may improve cardiovascular outcomes. An extensive and systematic review of the literature was carried out, and relevant findings presented in this review. There is evidence that T. violacea may modulate the renin-angiotensin system, the autonomic nervous system, oxidative stress and haemostasis, with resultant protection of the cardiovascular system in both health and disease.

Keywords: Tulbaghia violacea, Spontaneously hypertensive rats, Hypertension, Blood pressure, Heart rate, Renin-angiotensin aldosterone system




http://dx.doi.org/10.4314/tjpr.v14i6.25
AJOL African Journals Online