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Tropical Journal of Pharmaceutical Research

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Clinical effect of Fuzheng quyu therapy in patients undergoing radiotherapy after cervical carcinoma surgery

Ming-Zhu Liu, Hao Gu, Jin Xu, Rui-Tai Fan, Xiao-Ming Deng

Abstract


Purpose: To examine the clinical effect of Fuzheng Quyu therapy in patients undergoing radiotherapy after cervical carcinoma surgery.

Methods: One hundred and twenty patients who underwent radiotherapy after cervical carcinoma surgery were selected randomly and divided evenly into control and study groups. Patients in the control group underwent radiotherapy only, whereas those in the study group received treatment designed to nourish healthy vital energy and eliminate blood stasis in addition to radiotherapy. Changes in the coagulation index of the two groups were recorded after treatment. The clinical effects and the incidence of adverse events were compared between the groups.

Results: The plasma prothrombin time and activated partial thromboplastin time improved after treatment in the study group to greater extents than in the control group. The levels of D-dimer, blood platelets and fibrinogen were lower after treatment in the study group than in the control group (p < 0.05). Improvement in Karnofsky Performance Score and quality of life score of the study group was superior to that of the control group. The proportion of patients who required drug intervention was much lower in the study group (0.83 %) than in the control group (28.33 %) (p < 0.05). The incidence of adverse reactions was much lower in the study group (6.7 %) than in the control group (35.0 %, p < 0.05).

Conclusion: Herbal therapy designed to nourish vital energy and eliminates blood stasis relieves highlevel blood coagulation, and also improves quality of life (QoL) in patients undergoing radiotherapy after cervical carcinoma surgery, thus suggesting its potential clinical applications.

Keywords: Fuzheng, Blood stasis, Cervical carcinoma, Radiotherapy, Quality-of life




http://dx.doi.org/10.4314/tjpr.v16i1.29
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