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Tropical Journal of Pharmaceutical Research

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Testicular morphology and seminal fluid parameters of adult Wistar rats following honey administration

Eniola R Kadir, Lekan S Ojulari, Abdulmumin Ibrahim, Oluwole J Ekundayo, Rukayat Jaji-Sulaimon, Hidaayah O Jimoh-Abdulghaffaar

Abstract


Purpose: Honey has a long history of use in the traditional medical systems This objective of this study was to find out the effects of honey on quality and quantity of sperm and testicular microstructure when compared to fertility boosting drug and controls.
Methods: A total number of thirty (30) matured male Wistar rats that were sexually active weighing 200 - 280g were used for this study. The animals were grouped into five as A - E. Group A was the control; Group B (standard group) was the standard group that received 0.3ml of follicle stimulating hormone (FSH) drug for 6 days; groups C, D and E received 1ml, 2ml, and 2.5ml of honey daily for 21days respectively. After 21 days of administration, the testes were removed for analysis of the sperm parameters and the histology.
Results: Honey significantly improved the sperm quality and spermatogenesis rate (denser seminiferous tubule lumen) of exposed animals compared to control animals, but most improvement was seen in the standard group that received 0.3ml FSH. Also no sign of degeneration or cellular loss was observable in the testicular histo-architecture of experimental animals.
Conclusion: This research showed that honey possesses some fertility boosting properties in exposed animals compared to controls and honey is not associated with increased sperm abnormalities.

Keywords: Honey, Fertility booster, Spermatozoa, Ologospermia




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