Article Sidebar
Published:
Oct 29, 2013Keywords:
Article Details
Submission of a manuscript to this journal is a representation that the manuscript has not been published previously and is not under consideration for publication elsewhere.
All authors named in each manuscript would be required to sign a form (to be supplied by the Editor) so that they may retain their copyright in the article but to assign to us (the Publishers) and its licensees in perpetuity, in all forms, formats and media (whether known or created in the future) to (i) publish, reproduce, distribute, display and store the contribution, (ii) translate the contribution into other languages, create adaptations, reprints, include within collections and create summaries, extracts and/or abstracts of the contribution, (iii) create any other derivative works(s) based on the contribution, (iv) to exploit all subsidiary rights in the contribution, (v) the inclusion of electronic links from the contribution to third party material where-ever it may be located, and (vi) license any thrid party to do any or all of the above.
Main Article Content
Investigation of Association between Slime Production by <i>Candida Spp</i> and Susceptibility to Fluconazole and Voriconazole
Abstract
Purpose: To determine the susceptibilities of fluconazole and voriconazole based on slime production by Candida spp.
Methods: Candida strains (115) isolated in the period between January 2011 and January 2012 were included in this study. Conventional methods were used for the identification. Candida albicans and non-C. albicans isolates were tested for slime production with modified tube adherence test and antifungal resistance with disk diffusion method.
Results: Slime positivity was 31.3 % in all Candida species. Slime positivity in non-C.albicans isolates (44.89 %) was higher than in C. albicans species (21.21 %). All C. albicans isolates were sensitive to fluconazole and voriconazole. The highest resistance to fluconazole (40 %) and voriconazole (5%) was by C. glabrata strains.
Conclusion: Species definition and determination of antifungal susceptibility patterns are advised for the proper management and treatment of patients.
Keywords: Candida, Fluconazole, Voriconazole, Antifungal susceptibility, Slime
