Effects of oral contraceptives on total serum proteins, albumin, globumins and cholesterol levels in Ibadan, Nigeria

  • KA Obisesan Department of Obstetrics and Gynaecology, College of medicine University of Ibadan
  • FA Adenaike Department of Chemical Pathology and Haematology, Obafemi Awolowo College of Health Sciences, Ogun State University, Ago-Iwoye, Nigeria
  • MA Okunlola Department of Obstetrics and Gynaecology, College of medicine University of Ibadan
  • AA Adenaike Department of Chemical Pathology and Haematology, Obafemi Awolowo College of Health Sciences, Ogun State University, Ago-Iwoye, Nigeria

Abstract

Total serum, albumin, globulin, albumin/globulin ratio and cholesterol levels were determined in 25 subjects on oral contraceptives and 25 controls. The mean serum total protein, globulin and cholesterol levels were significantly increased in oral contraceptive and their control counterparts. The albumin/globulin ratio in subjects on oral contraceptives users is significantly decreased compared with controls. In view of the finding of this study, it is suggested that the biochemical profile of long-term oral contraceptive users be assessed periodically.

Résumé

Sérum protéine totale, albumine, globuline, le rapport albumine/globuline et le niveau du cholestérol tous étaient determines chez 25 clients, en utilisant contraceptives oraux (vaccin) buccal; et 25 des cas témoins.

La moyenne sérume protéine totale, globuline et le niveau du cholesterol avait été manifestement augumentés sur contraceptives oraux et chez les cas témoins contre-parties. Le rapport albumine/globuline chez les clients qui utilisent les contraceptives oraux était en baisse par rapport aux cas témoins.

Prenant les resultants de cette étude en consideration nous proposons qui l'on entre prend l'evaluation périodique d'un enregistrement biochimique à long terme des utilisateurs des contraceptives oraux.

West African Journal of Medicine Vol.21(3) 2002: 197-199

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