HIV-seroprevalence among pulmonary tuberculosis patients in a tertiary care hospital in Douala, Cameroon

  • Bertrand Hugo Mbatchou Ngahane
  • Henry Luma
  • Yacouba Mapoure Njankouo
  • Martine Nida
  • Achu Joko
  • Marthe Mbenoun
  • Samuel Wato
  • Albert Mouelle Sone

Abstract

A retrospective study was carried out at Douala General Hospital, Cameroon, between July 2007 and July 2011, to determine the prevalence of HIV infection among the pulmonary tuberculosis (pTB) patients and to compare epidemiological profiles with respect to TB/HIV co-infection. The cases of all patients aged 15 years and above and diagnosed with pTB during the study period were reviewed. Sociodemographic data, sputum examination for acid-fast bacilli, previous TB-treatment status, and HIV status were recorded. The chi-square or Fisher’s exact tests were used to compare the proportions. The independent sample t-test was used to compare means for the quantitative data. Of the 383 pTB patients included, 56.1% were males. The mean age was 38.9 ± 13.9 years (range 15–95). The age group 25–44 years was most represented, with 55.6% of the patients, while the least represented age group was that of patients over 65 years. The mean age of the females (36.2 ± 13.6 years) was statistically lower than that of the males (41.1 ± 13.8 years). Smear-positive pTB was diagnosed in 208 cases (54.6%). All the patients were tested for HIV infection. The overall prevalence of HIV among the pTB patients was 50.4%. There were no significant differences between the HIV-positive and HIV-negative groups with respect to age, sex, sputum examination for acid-fast bacilli, and previous TB-treatment status. The results suggest that the TB/HIV co-infection rate in Cameroon is high. Intensification of the screening of HIV infection in the general population and early management of HIV disease, especially in young women, could reduce the incidence of TB.

Keywords: co-infection, epidemiology, health management, quantitative research, screening, sub-Saharan Africa

African Journal of AIDS Research 2012, 11(4): 349–352

Author Biographies

Bertrand Hugo Mbatchou Ngahane
Douala General Hospital, Internal Medicine, PO Box 4856, Douala, Cameroon; University of Douala, Faculty of Medicine and Pharmaceutical Sciences, PO Box 2701, Douala, Cameroon
Henry Luma
Douala General Hospital, Internal Medicine, PO Box 4856, Douala, Cameroon
Yacouba Mapoure Njankouo
Douala General Hospital, Internal Medicine, PO Box 4856, Douala, Cameroon; University of Douala, Faculty of Medicine and Pharmaceutical Sciences, PO Box 2701, Douala, Cameroon
Martine Nida
University of Douala, Faculty of Medicine and Pharmaceutical Sciences, PO Box 2701, Douala, Cameroon
Achu Joko
Douala General Hospital, Internal Medicine, PO Box 4856, Douala, Cameroon
Marthe Mbenoun
University of Douala, Faculty of Medicine and Pharmaceutical Sciences, PO Box 2701, Douala, Cameroon
Samuel Wato
Douala General Hospital, Internal Medicine, PO Box 4856, Douala, Cameroon
Albert Mouelle Sone
Douala General Hospital, Internal Medicine, PO Box 4856, Douala, Cameroon; University of Douala, Faculty of Medicine and Pharmaceutical Sciences, PO Box 2701, Douala, Cameroon
Published
2013-01-11
Section
Articles

Journal Identifiers


eISSN: 1608-5906
print ISSN: 1727-9445