African Journal of Biomedical Research

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Anti-inflammatory and anti-nociceptive effects of ethanolic extract of Setaria megaphylla leaves in rodents

JE Okokon, B Anitia, BN Ita


The ethanolic leaf extract of Setaria megaphylla (100-300 mg/kg) was
investigated for pharmacological properties against egg white albumin - induced inflammation, Chemical as well as thermal- induced pain. The extract
demonstrated a dose – dependent anti- inflammatory and antinociceptive
activities. These activities were comparable to that of ASA (100mg/kg). The leaf extract possess anti inflammatory and analgesic properties, which can be
exploited in health care (Afr. J. Biomed. Res. 9: 229 – 233)

Keywords: Setaria megaphylla, anti inflammatory, analgesic.
AJOL African Journals Online