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African Journal of Traditional, Complementary and Alternative Medicines

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A study on the effect of resveratrol on lipid metabolism in hyperlipidemic mice

HC Xie, HP Han, Z Chen, JP He

Abstract


Background: The content of resveratrol is relatively high in Polygonum cuspidatum Sieb. et Zucc., and the resveratrol has the effect of blood vessel dilating, microcirculation improving, platelet aggregation inhibiting and anti-cancer. The objective of this paper was to study the effect of resveratrol on lipid metabolism in hyperlipidemia mice.
Materials andMethods: Through the establishment of an experimental mouse model of hyperlipidemia, the effect of resveratrol on change in total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-c), and low-density lipoprotein cholesterol (LDL-c) levels in mouse serum were determined.
Results: Resveratrol group can apparently reduce TC, TG, LDL-c and AI of hyperlipidemic mice in a dose effect manner.
Conclusion: We concluded that resveratrol can effectively reduce blood lipid levels of hyperlipidemic mice.

Keywords: Resveratrol; hyperlipidemia; TC; TG; HDL-c; LDL-c




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