African Journal of Urology

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Case report Primary extragonadal seminoma arising from the pelvis: A case report

C. Drachama, A. Elangovan, R. Madana, N. Gupta


Introduction: Extragonadal germ cell tumors (EGCT) are relatively rare tumors with an incidence of 2–5% among all germ cell tumors and commonly seen in males. They appear mostly in midline locations, commonly in the retroperitoneum, mediastinum and central nervous system but the origin of EGCTs remain controversial.
Observation: In this case report, we present a young male with prior history of right orchidectomy for undescended testis, presented as retroperitoneal mass arising from the true pelvis. Imaging studies revealed a large mass arising in the pre-sacral region within the pelvis. Fine Needle Aspiration Cytology and Immunocytochemistry studies revealed Seminoma of classical type. The patient was treated with chemotherapy and radiotherapy, presently no evidence of disease and on routine followup.
Conclusion: This is a unique case because to the best of our knowledge, only a few cases have been reported in the literature on EGCT (seminoma in present case) presenting as a pelvic mass. Seminoma in true pelvis should be considered as a differential diagnosis when pelvic mass is detected, even in post orchidectomy cases. Tumor markers, histology, and immunohistochemistry examinations are important in making an accurate diagnosis and providing appropriate treatment.
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