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Exploitable options for curbing the danger of SARS-CoV-2 in Africa


L. Yusuf
J. A. Bala
I. A. Aliyu
I. M. Kabir
M. W. Haruna

Abstract

Background: It is understood that coronavirus is highly mutated, in December, 2019 a new strain of coronavirus emerged which originated in Wuhan, from seafood. The pathogen was named novel coronavirus, while the disease it causes is known as Covid-19, the 2019 coronavirus disease. Bat is the major reservoir host of the virus. By putting bats in touch with other mammals will promote viral spillovers, which is a dominant condition for SARS-CoV-2, while also the effect of climate anomalies on food scarcity, behavioral flexibility, and bat immune modulation is likely to increase the risk of disease emergence. Over 34 million Covid-19 cases were registered between 31st of December 2019 and October 1st 2020 with Africa reporting about 1.4 million cases in this period.


Aim: This review was design to highlight possible options that can be exploited in curbing the Covid-19 menace in Africa.


Method: We reviewed articles from online databases for relevant documents written in English language. These includes NCBI, PubMed and Google scholar. We included both original and review papers that provided information on current SARS-CoV-2 trends and meta-analysis in Africa and globally.


Results: Of the 15 articles selected from the 128 available citations, approximately 40 million people worldwide have been diagnosed with SARS-CoV-2, while only 1.4 million people in Africa have been confirmed to be positive for the virus as of October 1, 2020, although the prevalence in Africa is low in relative to other continents. However, most African nations do not have the economy to buy the vaccines that are accessible. The availability of phytoterapeutic agents, on the other hand, would provide a cost-effective way to tackle the Covid-19 threat in Africa.


Conclusion: Cell lines adaptation in vaccine production, proteomic analysis of the viralhost interactomes, treatment approaches using natural occurring compounds, which will provide cost effective options to low-income countries can be adopted to curb the menace of Covid-19 in Africa.


Journal Identifiers


eISSN: 2635-3792
print ISSN: 2545-5672