Article Sidebar
Published:
May 22, 2014Keywords:
Article Details
Bio-Research journal is an open access journal, which means all its content is freely available without charge to the user or his/her institution.
You are free to share (that is, copy and redistribute the material in any medium or format) as long as you follow these licence terms:
Attribution (by)
You must give appropriate credit, provide a link to the license.
Non Commercial (nc)
You can copy, distribute, display, perform, and use this material for any purpose other than commercially (unless you get permission first). Non Commercial means not primarily intended for or directed towards commercial advantage or monetary compensation.
No Derivatives (nd)
If you remix, transform, or build upon the material, you may not distribute the modified material. But note that simply changing the format does not create a derivative.
No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the licence permits.
Notices
You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation.
Main Article Content
Effect of Simultaneous Administration of Antiretroviral Therapy and Nutritional Supplements on Cd4 Count of HIV-Infected Persons in Selected Communities of South Eastern Nigeria
Abstract
The simultaneous effect of highly active anti-retroviral therapy (HAART) and nutritional supplements on cluster of differentiation4 (CD4)count of 100 people living with HIV/AIDS (PLWHA) was investigated. CD4 cell count was determined using the Cyflow SL-3. Individuals with baseline CD4 counts less than 200 cells/ìl were placed on HAART for a period of 8 weeks at 4 weekly intervals. Total white blood cell (TWBC), haemoglobin (Hb)/ packed cell volume (PVC) were estimated using Sysmex KX-21N automated machine; Body mass index (BMI) calculated using World Health Organization’s BMI Reference Standards. Dietary intake and feeding history were recorded, followed by a 24 hourly dietary recall with Recommended Dietary Intake [RDA] of ELERON nutritional supplement. Eighty-one percent of treated subjects had increased CD4 count (P<0.05): TWBC had 24% increase; mean value (P<0.05). Haemoglobin and PCV showed significant increase (P < 0.05) at 5% or 10% levels. Concomitant effect of HAART and nutritional supplements on the CD4 count, Hb/PCV, BMI were significant at 5% or 10% levels. Mean BMI value was highly significant (20.23 kg/m2) compared with 16.40 kg/m2 (P=0.004). Immunological reconstitution of patients was observed following improved nutritional supplementation with HAART as effective adjunctive therapy/or clinical outcome-enhancer for PLWHA in rural and resource poor communities.
Keywords: Antiretroviral therapy, CD4 Count, Nutritional Supplement, HIV/AIDS
