Article Sidebar
Article Details
Bio-Research journal is an open access journal, which means all its content is freely available without charge to the user or his/her institution.
You are free to share (that is, copy and redistribute the material in any medium or format) as long as you follow these licence terms:
Attribution (by)
You must give appropriate credit, provide a link to the license.
Non Commercial (nc)
You can copy, distribute, display, perform, and use this material for any purpose other than commercially (unless you get permission first). Non Commercial means not primarily intended for or directed towards commercial advantage or monetary compensation.
No Derivatives (nd)
If you remix, transform, or build upon the material, you may not distribute the modified material. But note that simply changing the format does not create a derivative.
No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the licence permits.
Notices
You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation.
Main Article Content
Studies on the Effects of Electrolytes and pH Control on the Lipophilicity of Fexofenadine Hydrochloride
Abstract
The effects of electrolytes and pH control on the lipophilic character of fexofenadine hydrochloride was investigated at room temperature. The study was performed by partitioning the drug between 1-octanol and water system. The water system consists of either electrolyte solution of varying concentrations or water adjusted to varying pH values. The most lipophilic effect was observed with aluminum chloride while the least drug lipophilicity was seen with sodium fluoride. The study also showed that pH control had no significant effect on the lipophilicity of fexofenadine hydrochloride.
Bio-Research Vol. 6 (1) 2008: pp. 301-302
