Carcinoma Of The Urinary Bladder In Maiduguri, Nigeria: A Retrospective Histopathological Study Of 100 Cases
AbstractAIMS: This study was conducted with the aim of determining the histopathological pattern, age and sex distribution of 100 cases of carcinoma of the urinary bladder in Maiduguri as well as highlight some of the associated aetiological factors.
METHODS: One hundred urinary bladder biopsies were received in the department of histopathology of the U M T H, Maiduguri. The specimens were previously fixed in 10% formalin. They were processed, sectioned and stained with standard haematoxylin and eosin stains. The records of patients were collected from our surgical daybooks. Patients with incomplete demographic data as well as Metastatic carcinomas were excluded from the study. Simple statistical analysis was used in analyzing the cases.
RESULTS: Squamous cell carcinoma was the commonest tumour and accounted for 70% of the cases. Transitional cell carcinoma constituted 22%. The least common tumours were embryonal rhabdomyosarcoma and carcinosarcoma contributing one case each.
Of the 70 cases of squamous cell carcinoma, 41 cases (58.6%) had associated vesical schistosomiasis. Fifty nine percent of cases were in the fifth and sixth decades of life. The tumour is three times more common in males than in females.
CONCLUSION: The high frequency of association of carcinoma of the bladder with schistosomiasis in our environment calls for serious attention by our clinicians to the eradication of schistosomiasis. This will by far reduce the number of cases of urinary bladder carcinoma associated with schistosomiasis.
KEY WORDS: Carcinoma of the urinary bladder; Histopathological pattern; Squamous cell; Schistosomiasis.
Highland Medical Research Journal Vol.2(1) 2004: 41-44