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The development and use of an inactivated vaccine against animals trichophytosis


Mynbay Umitzhanov
Aitkali Imanbaev
Gulmira Janabekova
Ainur Dzhangabulova
Symbat Usmangaliyeva

Abstract

Background: The annual increase in the number of camels entails a parallel increase in the incidence of trichophytosis,
which poses a great threat to the health and life of both this species of animals and other organisms that contact and
surround them.
Aim: The aim of the study was to develop and establish the quality of vaccines inactivated by ultrasonic exposure for
the prevention and treatment of trichophytosis in camels, and to compare them with chemically deactivated vaccines.
Methods: The peculiarity of the technology of production of these vaccines was the use of an innovative method of
inactivation of fungal strains by ultrasonic waves, which allowed to achieve high positive results in theory, and was
subsequently confirmed in practice by immunizing sick and healthy animals. The first tests of the obtained vaccines
were conducted in laboratory conditions on experimental rabbits.
Results: The results of prophylactic and therapeutic vaccinations were one hundred percent positive, which made it
possible to conduct further tests directly on camels of industrial farms, the expected result of which was also positively
confirmed at the end of the research.
Conclusion: As a result of this experiment, the effectiveness, stability, and safety of the manufactured vaccines were
established, which made it possible to approve the regulatory and technical documentation and patent them as an
innovative and effective development for the prevention and treatment of camel trichophytosis, which will reduce
the growth of infection and further overcome the mass spread of the disease both among camels and among the
surrounding organisms to which it is transmitted


Journal Identifiers


eISSN: 2218-6050
print ISSN: 2226-4485