Research Journal of Health Sciences

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The effect of pyridoxine supplementation on quality of life of patients with chronic lymphocytic leukaemia

I.A. Nwannadi, M.A. Onoja, U.S. Anike, I.H. Aba, R Okoli, I. Okolie, M. Aondover, E. Kyoive, O.O. Alao


Objective: Pyridoxine, is essential in the metabolism of many classes of food, we aimed at determining the effect of its supplementation on the quality of life (QoL) of patients with chronic lymphocytic leukaemia (CLL).
Methods: This study compared the (QoL) and haematological parameters of CLL patients before and after the administration of pyridoxine. Data obtained were analyzed using SPSS version 19.
Results: There was improvement in the QoL of the patients after pyridoxine supplementation; Majority of the parameters that make up the physical functional scales was significantly higher after pyridoxine supplementation. There were also significant improvements in insomnia, appetite loss and constipation after pyridoxine supplementation.
Conclusion: Pyridoxine supplementation in patients with CLL marginally improved quality of life.

Keywords: Pyridoxine, Supplementation, Quality of life, Leukaemia, CLL
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