An Expedient Method for the Synthesis of Acylhydrazones under Microwave Irradiation in Solvent-free Medium
A simple, efficient and eco-friendly method for the synthesis of acylhydrazones from acylhydrazides and aldehydes under microwave (MW) irradiation was reported, no solvent and catalyst was used. The method is combined with a combinatorial approach and fourteen novel acylhydrazones were synthesized in excellent yields (89–96%) and short reaction times (less than 5 min).
KEYWORDS: Acylhydrazides, acylhydrazones, acylhydrazones, microwave, solvent-free.
Copyright for articles published in this journal is retained by the journal.
SAJChem applies the Creative Commons Attribution (CC BY) license to manuscripts we publish. This license was developed to facilitate open access – namely, free immediate access to, and unrestricted reuse of, original works of all types. Under this license, authors agree to make articles legally available for reuse, without permission or fees, for virtually any purpose. Anyone may copy, distribute or reuse these articles, as long as the author and original source are properly cited.