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One-Pot, Simple and Efficient Synthesis of Triaryl-1H-imidazoles by KMnO<sub>4</sub>/CuSO<sub>4</sub>
Abstract
2,4,5-Triarylimidazoles have been obtained in excellent yields by the one-pot three-component condensation of bis-aryl α-hydroxyketones, aromatic aldehydes and ammonium acetate by the action of inexpensive, readily available and nontoxic KMnO4/CuSO4 under mild reaction conditions. The present method is simple, efficient, cost-effective and eco-friendly.
KEYWORDS Triarylimidazoles, Three-component reaction, One-pot synthesis, Oxidation, bis-aryl á-hydroxyketone, KMnO4, CuSO4.
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