A Convenient and Direct Route to 1,2-Dichlorovinylphosphine Oxides via Copper-catalyzed addition of H-phosphine Oxides to 1,2-Dichloroethyne
An efficient, convenient and inexpensive CuI-catalyzed method for the synthesis of 1,2-dichlorovinylphosphine oxides from substituted phosphites, diphenylphosphine oxide and 1,2-dichloroethyne has been developed in moderate-good yields, and the reactions provided mainly regioselective anti addition products.
Keywords: Copper-catalyzed addition reaction, 1,2-dichlorovinylphosphine oxides
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