Antioxidant, antidiabetic and antibacterial activities of <i>Ricinus communis</i> root extracts

Abstract

Present study investigated antioxidant, antidiabetic and antibacterial effectiveness of Ricinus communis root. Total phenols content (TPC), total flavonoid contents (TFC) and antioxidant activity were determined by folin-ciocalteu reagent method, aluminium chloride colorimetric technique and 2, 2-diphenyl l- picrylhydrazyl (DPPH) scavenging assay respectively. Antiglycation, alpha amylase inhibition, and antibacterial analyses were done by prescribed procedures. Methanol fraction had significant (P<0.05) TPC (90± 0.19 mg/g GAE) and TFC (32 ± 0.85 μg/mL CE) along with significant (P<0.05) antioxidant activities (41-42%). Extracts presented optimal antidiabetic and antimicrobial efficacies validating therapeutic properties of R.communis root.