Theoretical model analysis of molecular orientations in liquid protein dielectrics
In this study, some theoretical model functions have been used to explain the molecular behaviour of four different types of proteins; human haemoglobin, Insulin, egg-white lysozyme and β - globulin molecules in solution. The results of the computational fitting procedures showed that the dielectric dispersion of the protein molecules generally followed the Debye and Cole-Cole functions. The dielectric parameters obtained from the dispersions, relating to the structural and electrical properties of the molecules were tabulated. The relationships between the dispersion amplitude Δ and the molecular dipole moment μ of the proteins and also between the relaxation time τ and the energy of activation ΔH of the molecules have been highlighted. The molecular interpretation of the polarization effects responsible for the dielectric dispersions have been discussed.
Journal of the Nigerian Association of Mathematical Physics Vol. 10 2006: pp. 15-20